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reReg - Recurrent Event Regression

A comprehensive collection of practical and easy-to-use tools for regression analysis of recurrent events, with or without the presence of a (possibly) informative terminal event described in Chiou et al. (2023) <doi:10.18637/jss.v105.i05>. The modeling framework is based on a joint frailty scale-change model, that includes models described in Wang et al. (2001) <doi:10.1198/016214501753209031>, Huang and Wang (2004) <doi:10.1198/016214504000001033>, Xu et al. (2017) <doi:10.1080/01621459.2016.1173557>, and Xu et al. (2019) <doi:10.5705/SS.202018.0224> as special cases. The implemented estimating procedure does not require any parametric assumption on the frailty distribution. The package also allows the users to specify different model forms for both the recurrent event process and the terminal event.

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openblascpp

5.78 score 23 stars 2 dependents 44 scripts 443 downloads

aftgee - Accelerated Failure Time Model with Generalized Estimating Equations

A collection of methods for both the rank-based estimates and least-square estimates to the Accelerated Failure Time (AFT) model. For rank-based estimation, it provides approaches that include the computationally efficient Gehan's weight and the general's weight such as the logrank weight. Details of the rank-based estimation can be found in Chiou et al. (2014) <doi:10.1007/s11222-013-9388-2> and Chiou et al. (2015) <doi:10.1002/sim.6415>. For the least-square estimation, the estimating equation is solved with generalized estimating equations (GEE). Moreover, in multivariate cases, the dependence working correlation structure can be specified in GEE's setting. Details on the least-squares estimation can be found in Chiou et al. (2014) <doi:10.1007/s10985-014-9292-x>.

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openblascpp

4.75 score 4 stars 3 dependents 31 scripts 408 downloads

tranSurv - Transformation-Based Regression under Dependent Truncation

A latent, quasi-independent truncation time is assumed to be linked with the observed dependent truncation time, the event time, and an unknown transformation parameter via a structural transformation model. The transformation parameter is chosen to minimize the conditional Kendall's tau (Martin and Betensky, 2005) <doi:10.1198/016214504000001538> or the regression coefficient estimates (Jones and Crowley, 1992) <doi:10.2307/2336782>. The marginal distribution for the truncation time and the event time are completely left unspecified. The methodology is applied to survival curve estimation and regression analysis.

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3.48 score 2 stars 15 scripts 266 downloads

pseudoCure - A Pseudo-Observations Approach for Analyzing Survival Data with a Cure Fraction

A collection of easy-to-use tools for regression analysis of survival data with a cure fraction proposed in Su et al. (2022) <doi:10.1177/09622802221108579>. The modeling framework is based on the Cox proportional hazards mixture cure model and the bounded cumulative hazard (promotion time cure) model. The pseudo-observations approach is utilized to assess covariate effects and embedded in the variable selection procedure.

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openblascpp

3.30 score 4 scripts 125 downloads

spef - Semiparametric Estimating Functions

Functions for fitting semiparametric regression models for panel count survival data. An overview of the package can be found in Wang and Yan (2011) <doi:10.1016/j.cmpb.2010.10.005> and Chiou et al. (2018) <doi:10.1111/insr.12271>.

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2.70 score 1 stars 9 scripts 232 downloads